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DPS Staff

Ozempic: A Potential Addiction Cure?



In recent months, Ozempic has been making headlines for its weight loss effects in treating type 2 diabetes.


The use of Ozempic and Wegovy - a class of medications called GLP-1 agonists, which contain the active compound semaglutide - has also been reported to reduce addiction in a growing number of users.


Some users say the medication has reduced their hunger and satiety, but also stopped them from smoking, gambling, and drinking. Other users have reported that Ozempic helped them curb habits such as online shopping and nail-biting.


Users of the drug are sharing testimonials on social media platforms like TikTok, saying they no longer desire to engage in these activities after taking the drug.


What is Ozempic and How Does it Work?


In adults suffering from type 2 diabetes, Ozempic (semaglutide) is a once-weekly injectable medication that helps improve blood sugar control. Additionally, it is approved as a treatment to prevent major cardiovascular events such as heart attacks, strokes, and death in adults who have type 2 diabetes and known heart disease.


By mimicking glucagon-like peptide-1 (GLP-1), Ozempic works by promoting weight loss. It helps regulate blood sugar levels by a number of mechanisms after eating:

  • In addition to lowering blood sugar levels, it stimulates the pancreas to release insulin.

  • Through its ability to inhibit glucagon release from the pancreas, it prevents blood sugar levels from rising to dangerous levels.

  • When you eat, it slows down the emptying of the stomach, resulting in a feeling of fullness.

Ozempic is not a weight loss medicine. However, it is safe and effective for Type 2 diabetes, and it can lead to weight loss. Taking Ozempic if you are not diabetic is known as off-label use.


It can take up to 8 weeks for Ozempic to fully take effect. Generally, blood sugar levels start to improve within the first week of taking the pill.


Some side effects of Ozempic can include nausea, vomiting, diarrhea, and constipation. In most cases, these side effects are mild and disappear within a few days. In any case, you should consult your physician if you experience any severe side effects.


How Could Ozempic Help With Addiction?


Recent research has shown that Ozempic may help with addictions. In addition to GLP-1 receptors in the reward center of the brain, which processes addictive stimuli, there are also GLP-1 receptors in the adrenal gland. Research has shown that Ozempic reduces food and alcohol cravings in some people.


For example, one study involving lab mice has shown “profound effects on cocaine-mediated behaviors.” Another study, funded by Ozempic's manufacturer, found that reward centers in the brains of people with alcohol use disorder who took a similar drug lit up less when told they would see pictures of alcohol.


“Patients do say that they feel a benefit on their addiction, whether it’s alcohol or smoking or anything like that. People are even saying they’ve decreased their gambling,” said Dr. Asim Shah, a professor and executive vice chair in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor. “Is it true or not? We don’t have proof.”


There is, however, still a need for more research on Ozempic's effectiveness in treating addictions. Currently, there has been no clinical trial specifically investigating Ozempic's ability to treat addiction.


As a possible remedy for addiction, Ozempic may help in the following ways:

  • Reduce cravings. Food, alcohol, and other substances may be reduced by Ozempic. A possible explanation is that it affects the reward center in the brain, which is responsible for processing addictive stimuli.

  • Increase satiety. By increasing satiety, Ozempic makes you feel full with less food. Weight loss may be stimulated by reducing food intake.

  • Improve mood. Ozempic can reduce anxiety and stress by enhancing mood. People who struggle with addiction may find this useful since stress and anxiety can trigger cravings.

The importance of this cannot be overstated. In terms of addiction, Ozempic is not a miracle cure. Therapy, and other treatment programs are still essential for lasting recovery. It is possible, however, that Ozempic could serve as a useful addition to a comprehensive treatment plan.


The Bottom Line


For people suffering from substance abuse or mental health concerns, there are safe, effective, and researched medications available. Getting more information on medication-assisted treatment and other treatment options can be had by contacting a treatment provider today.

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